Development and Characterization of Gallium-Doped Bioactive Glasses for Potential Bone Cancer Applications
- Submitting institution
-
Aston University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 23181433
- Type
- D - Journal article
- DOI
-
10.1021/acsbiomaterials.7b00283
- Title of journal
- ACS Biomaterials Science and Engineering
- Article number
- -
- First page
- 3425
- Volume
- 3
- Issue
- 12
- ISSN
- 2373-9878
- Open access status
- Deposit exception
- Month of publication
- September
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
5
- Research group(s)
-
B - Aston Institute of Urban Technology and the Environment (ASTUTE)
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This is the first report of a bioactive material that selectively kills bone cancer cells and simultaneously promotes new bone formation. A patent has been filed (http://www.sumobrain.com/patents/wipo/Therapeutic-material/WO2018099997A1.pdf). This work has received significant attention from clinitians (Royal Orthopaedic Hospital, Clinical Consultant) and veterinarians (Surgical Discovery Centre, Director). It has directly resulted in seven follow-on grants including an Innovate UK grant ICURE, a Sarcoma UK PhD studentship (£118,900), a RAEng/ Leverhulme Senior Research Fellowship (LTSRF1819\15\19) and industrial funding from Implantcast GmbH (£70,000, [details available]). It has led to international collaborations with in-vivo studies in Brazil and a Marie-Curie Fellowship.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
