Using Magnetic Nanoparticles for Gene Transfer to Neural Stem Cells: Stem Cell Propagation Method Influences Outcomes
- Submitting institution
-
University of Keele
- Unit of assessment
- 12 - Engineering
- Output identifier
- 446
- Type
- D - Journal article
- DOI
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10.3390/jfb6020259
- Title of journal
- Journal of Functional Biomaterials
- Article number
- -
- First page
- 259
- Volume
- 6
- Issue
- 2
- ISSN
- 2079-4983
- Open access status
- Out of scope for open access requirements
- Month of publication
- April
- Year of publication
- 2015
- URL
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https://www.mdpi.com/2079-4983/6/2/259/htm
- Supplementary information
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-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
3
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- This work was supported by a BBSRC New Investigator Grant (BB/F013884/1) and EPSRC Centre for Doctoral Training Regenerative Medicine PhD. Here we reported novel 'magnetofection' for virus-free genetic engineering of transplant populations of neural stem cells. Technical approaches developed therein underpinned grant awards; EPSRC ETERM Fellowship (EP/I017801/1) for C Adams and BBSRC Research Grant (BB/J017590/1) for D Chari. The protocols have been adapted for other transplant cell types (i.e., olfactory ensheathing cells – Delaney et al., Nanoscale, 2017) and have featured in invited conference presentations (i.e., TCES Annual Conference, 2016). The work also underpinned C Adams appointment to Lecturer.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
