Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects
- Submitting institution
-
University of Keele
- Unit of assessment
- 12 - Engineering
- Output identifier
- 421
- Type
- D - Journal article
- DOI
-
10.1039/C7NR06794A
- Title of journal
- Nanoscale
- Article number
- -
- First page
- 11782
- Volume
- 10
- Issue
- 25
- ISSN
- 2040-3364
- Open access status
- Compliant
- Month of publication
- April
- Year of publication
- 2018
- URL
-
https://pubs.rsc.org/en/content/articlelanding/2018/nr/c7nr06794a#!divAbstract
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- No
- Number of additional authors
-
9
- Research group(s)
-
-
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- Collaborative work between Keele and Warwick Universities applied advanced x-ray spectromicroscopy to characterise the biochemistry of human Alzheimer’s disease pathology. The paper supported the award of two EPSRC funded projects (EP/N033140/1, EP/N033191/1) and a Kleberg Foundation grant (Principal investigator: Prof George Perry, University of Texas at San Antonio. See https://www.klebergfoundation.org/grant-guidelines/medical-research). This work featured in the UKRI’s impact of UK-US collaboration document, the Diamond Light source annual review (2018/2019) and led to an international conference presentation at XRM 2018 (Canada). Components of this work were included in the successfully defended PhD theses of Vindy Tjendana-Tjhin and Jake Brooks (University of Warwick).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
