Genome-wide association analyses of sleep disturbance traits identify new loci and highlight shared genetics with neuropsychiatric and metabolic traits
- Submitting institution
-
Aston University
- Unit of assessment
- 11 - Computer Science and Informatics
- Output identifier
- 21499963
- Type
- D - Journal article
- DOI
-
10.1038/ng.3749
- Title of journal
- Nature Genetics
- Article number
- -
- First page
- 274
- Volume
- 49
- Issue
- 2
- ISSN
- 1061-4036
- Open access status
- Compliant
- Month of publication
- December
- Year of publication
- 2016
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- 5 - Biological Sciences
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
19
- Research group(s)
-
A - Aston Institute of Urban Technology and the Environment (ASTUTE)
- Citation count
- 122
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- First very large-scale study of influence of genetic factors on sleep behaviours relevant to cardio-metabolic and mental illnesses. This study identifies novel genetic relationships between sleep duration, schizophrenia and measures of adiposity (BMI, waist circumference). The findings have motivated a lot of further work on genome-wide studies analysing the relationship between sleep behaviours and disorders related to learning abilities, mental health, metabolic conditions and others.
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
