An Acoustic On-Chip Goniometer for Room Temperature Macromolecular Crystallography
- Submitting institution
-
Aston University
- Unit of assessment
- 12 - Engineering
- Output identifier
- 29415916
- Type
- D - Journal article
- DOI
-
10.1039/C7LC00812K
- Title of journal
- Lab on a Chip
- Article number
- -
- First page
- 4225
- Volume
- 17
- Issue
- 24
- ISSN
- 1473-0197
- Open access status
- Compliant
- Month of publication
- November
- Year of publication
- 2017
- URL
-
-
- Supplementary information
-
-
- Request cross-referral to
- -
- Output has been delayed by COVID-19
- No
- COVID-19 affected output statement
- -
- Forensic science
- No
- Criminology
- No
- Interdisciplinary
- Yes
- Number of additional authors
-
9
- Research group(s)
-
B - Aston Institute of Urban Technology and the Environment (ASTUTE)
- Proposed double-weighted
- No
- Reserve for an output with double weighting
- No
- Additional information
- In this paper we report a completely new method of probing protein crystals at room temperature in a simple way (using acoustics). This work represents a step towards time-resolved crystallography where changes in protein structure in the presence of reagents can be observed. The work has informed other research on acoustic droplet manipulation for MX techniques (DOI: 10.1038/s41598-019-48612-4).
- Author contribution statement
- -
- Non-English
- No
- English abstract
- -
